Pascale Varlet Selected Research

Ganglioglioma

2/2020	Rapid fully-automated assay for routine molecular diagnosis of BRAF mutations for personalized therapy of low grade gliomas.
1/2019	H3F3A-G34R mutant high grade neuroepithelial neoplasms with glial and dysplastic ganglion cell components.
1/2018	Co-occurrence of histone H3 K27M and BRAF V600E mutations in paediatric midline grade I ganglioglioma.
4/2017	Epileptic seizures in anaplastic gangliogliomas.
7/2015	An Unusual Case of Constitutional Mismatch Repair Deficiency Syndrome With Anaplastic Ganglioglioma, Colonic Adenocarcinoma, Osteosarcoma, Acute Myeloid Leukemia, and Signs of Neurofibromatosis Type 1: Case Report.
6/2014	Vemurafenib in pediatric patients with BRAFV600E mutated high-grade gliomas.

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Pascale Varlet Research Topics

Disease

57	Neoplasms (Cancer) 11/2022 - 12/2004
35	Glioma (Gliomas) 10/2022 - 12/2004
15	Glioblastoma (Glioblastoma Multiforme) 11/2022 - 01/2011
13	Medulloblastoma 01/2021 - 05/2009
8	Diffuse Intrinsic Pontine Glioma 04/2020 - 01/2012
6	Brain Neoplasms (Brain Tumor) 04/2020 - 01/2011
6	Ganglioglioma 02/2020 - 06/2014
4	Ependymoma 01/2022 - 04/2009
4	Oligodendroglioma 01/2020 - 02/2010
3	Seizures (Absence Seizure) 11/2022 - 04/2017
3	Meningioma (Meningiomas) 04/2021 - 01/2018
3	Ganglion Cysts (Ganglion) 01/2019 - 12/2004
3	Primitive Neuroectodermal Tumors (PNET) 02/2016 - 08/2014
2	Hypertension (High Blood Pressure) 04/2022 - 01/2016
2	Astrocytoma (Pilocytic Astrocytoma) 01/2021 - 01/2020
2	Lymphoma (Lymphomas) 03/2018 - 01/2018
2	Carcinogenesis 10/2015 - 07/2014
2	Temporal Lobe Epilepsy 07/2014 - 03/2010
1	Proteinuria 04/2022
1	Brain Abscess (Abscess, Brain) 04/2022
1	Cysts 04/2022
1	Abscess 04/2022
1	Epistaxis (Nosebleed) 04/2022
1	Fatigue 04/2022
1	Angiomyoma (Angioleiomyoma) 01/2022
1	Rhabdomyosarcoma 01/2022
1	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2022
1	Central Nervous System Neoplasms 01/2022
1	Nervous System Neoplasms (Neoplasms, Nervous System) 01/2022
1	Paraganglioma (Paragangliomas) 12/2021
1	Pleomorphic Adenoma 11/2021
1	Neurologic Manifestations (Neurological Manifestations) 01/2021
1	Disease Progression 11/2020
1	Neuroepithelial Neoplasms (Gliomatosis Cerebri) 02/2020
1	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 01/2019
1	Cytopenia 01/2019
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2019
1	Evans Syndrome 01/2019

Drug/Important Bio-Agent (IBA)

13	Histones (Histone)IBA 12/2021 - 10/2015
13	dipinacoline glutamateIBA 04/2020 - 01/2012
10	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2009
9	Biological ProductsIBA 12/2021 - 12/2004
7	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 11/2022 - 08/2014
6	Biomarkers (Surrogate Marker)IBA 06/2022 - 09/2010
6	Temozolomide (Temodar)FDA LinkGeneric 01/2020 - 02/2010
5	RNA (Ribonucleic Acid)IBA 11/2021 - 10/2017
4	Bevacizumab (Avastin)FDA Link 04/2022 - 01/2018
4	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 09/2010
3	CateninsIBA 01/2021 - 08/2012
3	Phosphotransferases (Kinase)IBA 01/2020 - 10/2018
3	ProteomeIBA 10/2018 - 11/2011
2	MethyltransferasesIBA 11/2022 - 12/2019
2	Irinotecan (Camptosar)FDA LinkGeneric 04/2022 - 04/2020
2	Carmustine (FIVB)FDA Link 04/2022 - 01/2015
2	Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA 01/2022 - 01/2021
2	ErbB Receptors (EGF Receptor)IBA 01/2022 - 01/2011
2	Epidermal Growth Factor (EGF)IBA 01/2022 - 10/2009
2	Lysine (L-Lysine)FDA Link 12/2021 - 11/2018
2	Etoposide (VP 16)FDA LinkGeneric 11/2020 - 01/2018
2	ParaffinIBA 02/2020 - 01/2012
2	Transcription Factors (Transcription Factor)IBA 12/2018 - 01/2018
2	TenascinIBA 01/2017 - 04/2009
2	gamma-Aminobutyric Acid (GABA)IBA 01/2017 - 07/2014
2	Neurofilament ProteinsIBA 09/2012 - 12/2004
2	beta CateninIBA 03/2011 - 05/2009
1	Levetiracetam (Keppra)FDA LinkGeneric 11/2022
1	2,6-dinitrotoluene (DNT)IBA 10/2022
1	Amyloid (Amyloid Fibrils)IBA 01/2022
1	human ERBB2 proteinIBA 01/2022
1	diazoluminolmelaninIBA 01/2022
1	Progestins (Progestagens)IBA 04/2021
1	Circular RNAIBA 01/2021
1	HhAntag691IBA 01/2021
1	sonidegibIBA 01/2021
1	SteroidsIBA 01/2021
1	CollagenIBA 01/2021
1	Carboplatin (JM8)FDA LinkGeneric 11/2020
1	Nonsense Codon (Nonsense Mutation)IBA 07/2020
1	Formaldehyde (Formol)FDA Link 02/2020
1	antiarrhythmic peptide (AAP)IBA 01/2020
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2020
1	Angiogenesis InhibitorsIBA 01/2020
1	O-(6)-methylguanineIBA 12/2019
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 01/2019
1	Inosine Triphosphate (ITP)IBA 01/2019
1	Complement System Proteins (Complement)IBA 01/2019
1	ChromatinIBA 01/2019
1	Intergenic DNA (Junk DNA)IBA 11/2018
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 03/2018
1	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2018
1	A-factor (Streptomyces)IBA 01/2018

Therapy/Procedure

18	Radiotherapy 11/2022 - 01/2011
12	Therapeutics 02/2020 - 04/2009
10	Drug Therapy (Chemotherapy) 11/2022 - 01/2012
2	Investigational Therapies (Experimental Therapy) 01/2011 - 02/2010
1	Chemoradiotherapy 04/2022
1	Conservative Treatment 04/2021
1	Neoadjuvant Therapy 11/2020
1	Time-to-Treatment 01/2020
1	Surgical Instruments (Clip) 01/2019